Two women executives in the automotive industry have made Fortune’s “50 Most Powerful Women in Business: Global Edition” list.

Mary Barra, the new CEO of General Motors, claims the No. 1 spot. As the first woman to run a global automaker, she manages more than 212,000 employees in 396 GM facilities on six continents, says Fortune.

And Pam Nicholson, the president and CEO of Enterprise Holdings, takes the 36th spot on the list. With rental locations in 50 countries, Nicholson is planning to continue overseas expansion into 70 countries and territories, says Fortune.

“By pushing into new territories and inspiring women in their home countries, these globetrotters are, quite literally, taking on the world,” according to Fortune.

Rounding out the top 10, the other powerful businesswomen to make Fortune’s list include Ginni Rometty (CEO, president of IBM), Indra Nooyi (chairman, CEO of PepsiCo), Maria das Gracas Silva Foster (ECO of Petrobras), Ellen Kullman (chairman, CEO of DuPont), Irene Rosenfeld (chairman, CEO of Mondelez International), Marillyn Hewson (chairman, president, CEO of Lockheed Martin), Meg Whitman (president, CEO of Hewlett-Packard), Patricia Woertz (chairman, CEO, president of Archer Daniels Midland) and Gail Kelly (managing director, CEO of Westpac).

For this first global edition of most powerful women in business, Fortune editors looked at factors including size and importance of the business, the arc of the leader’s career as well as the international aspect of the leader’s company.

Click here for Fortune’s full list of “50 Most Powerful Women in Business: Global Edition”: http://money.cnn.com/gallery/leadership/2014/02/06/global-most-powerful-women.fortune/index.html